Very cool video from the Kishony lab @ Harvard. Here we see evolution happening live and point mutation propagating overcoming the antibiotic gradient.
tdl:
OMG — watch bacterial evolution with your eyeballs!
This is a timelapse of an experiment in the Observatory of Mutation and Growth, a unique 4 foot x 2 foot petri dish built by the Kishony Lab.
Here, we have spotted bacteria on the sides of the observatory.
We set the bacteria up for an interesting challenge by putting the antibiotic trimethoprem in the dish in a particular pattern. Each vertical stripe towards the center of the plate has a 10fold higher concentration of trimethoprem (you can imagine it sort of like a hill of concentration).
Only the few lucky bacteria that have made the right errors while copying their DNA make it to the next stripe.
Then we took a video over the next 6 days time, 1 frame every 10 minutes. I’m so proud of it right now.
